Chemical Composition, Antimicrobial, Antioxidant and Anticancer Activity of Leaves of Syzygium benthamianum (Wight ex Duthie) Gamble

TitleChemical Composition, Antimicrobial, Antioxidant and Anticancer Activity of Leaves of Syzygium benthamianum (Wight ex Duthie) Gamble
Publication TypeJournal Article
Year of Publication2011
AuthorsKiruthiga K, Saranya J, Eganathan P, Sujanapal P, Parida A
JournalJournal of Biologically Active Products from Nature
Start Page273
End page278
Date Published2011
KeywordsAnticancer activity, antimicrobial, antioxidant, ethyl acetate extract, Journal of Biologically Active Products from Nature, Syzygium benthamianum
Abstract

The study was carried out on antimicrobial, antioxidant and anticancer activity of Syzygium
benthamianum leaf extract. Chemical compositions of the leaf were analysed using GC/MS technique. A total
of 24 compounds were identified among which 4-(4-ethylcyclohexyl)-1-pentyl-Cyclohexene (24.07 %) and
Linoleic acid (15.16 %) are the major constituents. Antimicrobial activity of the leaf was observed on six
bacterial and three fungal species, whose MIC values ranged from 100 to 500 μg/ml. At higher concentration,
the extract exhibits higher scavenging activity (94.7 %) that was comparable with standard BHT. It was also
observed that the leaf sample were able to effectively inhibit the growth of Hep 2 cells.
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Publisher Category: 
MSSRF Staff
Department: 
Bio-Technology